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2-day hypertrophy routine

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hypertrophy2 days/weekfree

A hypertrophy routine over 2 days is built to build muscle: enough sets per muscle group, close to failure, with a little more load each week.

Parameters the engine applies

ParameterValue
Assigned structureFull Body
Reps per set6-12
Sets per exercise3-4
Rest between sets60-180 s
RIR (reps in reserve)2-4
Intensity65-80% 1RM
Share of compound exercises65 %

These are not generic recommendations: they are the exact parameters the engine uses to build this routine, and they change with the goal you pick.

How your week looks

DaySession
Day 1Full Body A
Day 2Full Body B

The engine splits muscle groups across sessions according to the structure that matches your available days.

Exercise table: the week the engine builds

This is the routine Progrevia builds for an intermediate lifter with a full gym and 60-minute sessions: 10 exercises and 40 sets per week. Yours adapts to your level, your equipment and your time, so it may differ.

Day 1 · Full Body A

ExerciseSets × repsRIRRest
Incline bench press4 × 5-83-4150 s
Machine row4 × 5-83-4150 s
Dumbbell lunges4 × 5-83-4150 s
Sumo deadlift4 × 5-83-4150 s
Cable lateral raise4 × 8-153-4105 s

Day 2 · Full Body B

ExerciseSets × repsRIRRest
Machine row4 × 8-123-4120 s
Incline bench press4 × 8-123-4120 s
Good mornings4 × 8-123-4120 s
Sumo goblet squat4 × 8-123-4120 s
Cable lateral raise4 × 8-153-4105 s

Weekly sets per muscle group

Muscle groupSets per week
Back8
Glutes8
Shoulders8
Chest8
Quads4
Hamstrings4

Each set is counted on the exercise's main muscle. It is the most direct way to compare this routine with another: at equal effort, weekly volume is what weighs most on the result.

What changes compared with the 3-day routine

With 2 days the week adds up to 40 sets; with 3, 55. These are the differences per muscle group:

Sessions in the 3-day routine: Push, Pull, Legs.

Hypertrophy in 2 days: weekly sets, proximity to failure and progression

To build muscle, well-executed weekly volume matters most. In the meta-analysis by Schoenfeld, Ogborn and Krieger (2017, Journal of Sports Sciences), more weekly sets per muscle were associated with more growth, and 10 or more sets beat fewer than 5. Effort counts too: Robinson and colleagues (2024) found more hypertrophy the closer to failure sets ended. That is why the engine keeps few reps in reserve and raises volume gradually.

With 2 days, high volume per muscle is hard to reach: each full-body session trains everything, and what adds up is taking each set close to failure.

The week the engine builds has 2 sessions, 10 exercises and 40 sets in total. Counting sets and rest, each session takes about 55 minutes, not including the warm-up.

Your first four weeks on the 2-day hypertrophy routine
WeekWhat to doWhy
1Your 2 sessions (Full Body A, Full Body B) with sets at 3-4 reps in reserveDial in weights without piling up fatigue
2Same weight and more reps within the range, starting with incline bench press and sumo deadliftDouble progression: reps first, then load
3Sets closer to failure (1-2 in reserve) on isolation workMore stimulus where the risk is lower
4Add weight where you hit the top of the range; if fatigue builds, drop to about 24 of the 40 setsStart the next cycle with new loads
References
  1. Schoenfeld BJ, Ogborn D, Krieger JW. Dose-response relationship between weekly resistance training volume and increases in muscle mass: a systematic review and meta-analysis. Journal of Sports Sciences. 2017;35(11):1073-1082.
  2. Robinson ZP, Pelland JC, Remmert JF, Refalo MC, Jukic I, Steele J, Zourdos MC. Exploring the dose-response relationship between estimated resistance training proximity to failure, strength gain, and muscle hypertrophy: a series of meta-regressions. Sports Medicine. 2024;54(9):2209-2231.

How the week is split

Alternating full-body sessions (full body A and B): each works the big muscle groups with different exercises, spreading the stimulus without repeating the same session. This week, 4 of the 6 muscle groups with their own exercise are trained twice or more and 2 once.

What your routine includes

Who is this routine for?

That is 2 sessions of about 60 minutes, 2 hours a week, with 40 sets in total: about 20 per session. It fits if you can set aside those 2 days consistently; if not, look at the 3-day routine.

Exercises it usually includes

Other routines you may like

Generate yours for free

Progrevia creates your personalized hypertrophy routine of 2 days in under a minute, no mandatory sign-up and no card. With a free account you can download it as a PDF.

Learn the theory

Muscle hypertrophy: the 3 mechanisms that drive it

Frequently asked questions

How many days a week should I train?

It depends on your availability and recovery. 2 days a week is a balanced option for a hypertrophy goal.

Can I do the 2-day hypertrophy routine at home?

Yes. Muscle responds more to the effort of each set than to the type of equipment: with dumbbells, bands or bodyweight you grow if sets end close to failure. Progrevia adapts the exercise selection to what you have.

How long until the muscle shows?

Visible changes usually take 8-12 weeks of consistent training; before that, what goes up is strength. Measuring arms and legs every month gives a clearer signal than the mirror.

How many sets per week does the 2-day hypertrophy routine have?

40 sets spread over 10 exercises and 2 sessions. The group that gets the most work is back, with 8 weekly sets.

How many sets per muscle do I do each week on the 2-day hypertrophy routine?

The ones in the week the engine builds for your level; the volume table above shows this routine's numbers. The evidence suggests 10 or more weekly sets per muscle produce more growth than fewer than 5, as long as each set gets close to failure. Progrevia starts at a recoverable volume and raises it based on what you log. This week adds up to 40 sets over 2 sessions.

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